The American Journal of Nephrology is a peer-reviewed international journal that focuses on timely topics in both basic science and clinical research. Papers are divided into several sections, including: original reports, spanning clinical, basic, and outcomes research; in-depth topic reviews on specific topics selected by the editor and associate editors; invited debates, selected on “hot topics” determined by the editorial board. Responding to the ever-increasing pace in research, the American Journal of Nephrology adheres to a very tight publication schedule: accepted papers appear online in the unedited, original manuscript version within a few days of acceptance and the final version is published within 5-6 weeks of acceptance.